Mary Ann Smith
- Born: 13 Dec 1796, , Allegheny, Pennsylvania
- Marriage: Henry Keifer 29 Feb 1822 in , Allegheny, Pennsylvania
- Died: 14 Jan 1883 or 4 Jan 1893 at age 86
- Buried: Frankfort Springs Presbyterian Cemetery, , Beaver, Pennsylvania
 Noted events in her life were:
• Census: age 54, 1850, Hanover, Beaver, Pennsylvania.
• Census: age 62, 1860, Hanover, Beaver, Pennsylvania.
• Census: age 73, 1870, Hanover, Beaver, Pennsylvania.
• Census: age 84, living with son Robert Smith Keifer, 1880, Frankfort Springs, Beaver, Pennsylvania.
Mary married Henry Keifer, son of Johan Heinrich Kieffer and Anna Byers, 29 Feb 1822 in , Allegheny, Pennsylvania. (Henry Keifer was born on 22 May 1794 in Saint Clair, Allegheny, Pennsylvania, died in Dec 1878 and was buried in Frankfort Springs Presbyterian Cemetery, , Beaver, Pennsylvania.)
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